To make matters worse, despite it not being true, you bounce back to make it perfectly clear you haven't come here to seek advice but claim "I'm newly diagnosed with genital HSV-1." which is misleading. You have utterly disregarded these factoids, utterly disrespected those trying to advise you. Your pictures do not in any way resemble herpes lesions. You cannot become infected genitally with HSV-1 once you have an established oral infection and You have been told by people on this website: that No you have not come here at all seeking counsel and advice. At this stage, ABVIC is confirming that about 95% of WB indeterminates are negative. I understand that it has multiple phases that attempt to draw away antibodies not related to the type being tested for to create a purer sample for identifying if antibodies exist. The new Halford ABVIC test may eclipse the WB for accuracy. It was suspect that 95% of indeterminates were negative. This occurs owing to cross reaction of antibodies for the other type, non type specific antibodies and even some unrelated proteins altogether. An indeterminate result can occur when some bands respond. Most the results reveal either no antibodies or above threshold levels in all bands. Hence rather than just the one antigen (gG-2 for example), the WB has about 30 antigens that attract blood antibodies. Blood is introduced to the virus and I believe separated into at least four size bands of the antibodies found in the blood. Essentially the entire virus is used harvested in the UofW labs. It is the current gold standard in testing for herpes blood-borne antibodies. I'm a bit apathetic about certain details lately but, as far as I know, Univ of Washington is the only, if not one of few, lab that does the HSV W. It is the current gold standard HSV serology and provides a highly accurate confirmatory test for positive results by ELISA." This test has been exhaustively validated in studies of well-characterized patient populations. This method may be used to distinguish maternal from infant antibody profiles and to distinguish serum and cerebrospinal fluid profiles of HSV antibodies. The HSV Western blot uses HSV-1 and HSV-2 proteins which have been separated by size so that typespecific antibody profiles can be recognized with a specificity of >99%. Even commercial, FDA-cleared tests like the HerpeSelect ELISA from Focus Diagnostics-Quest may have false positive results, especially in samples with low positive readings. Halford has produced a new type of testing that would rival it.Īccurate assays to detect antibodies to HSV-1 and HSV-2 are useful to diagnose subclinical infections and to supplement virus detection methods in cases of atypical presentation or when sampling conditions are not optimal for virus recovery.ĬDC guidelines stipulate that only type-specific serologies based on glycoprotein G be used. It's the most accurate testing for HSV available. Sorry to be dumb but what is a western blot and what does it show differently from other testing.
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